Detroit to Kansas City
The Carolina Panthers, who had the worst record for the 2010 NFL season at 2–14, had the right to the first selection in each round of the draft. With the first pick the Panthers selected Auburn University quarterback Cam Newton, who was the 2010 Heisman Trophy winner.
A second Heisman Trophy winner, running back Mark Ingram from Alabama was selected by New Orleans late in the first round. This was the eleventh draft which included multiple Heisman winners, and the first time ever that it has occurred in consecutive drafts. Five of the first six picks played college football in the Southeastern Conference.
For the second consecutive year—and the third time in NFL history—the top two selections of the draft won Offensive and Defensive Rookie of the Year awards, respectively.
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